Article
Genetic variations in the ADAMTS12 gene are associated with schizophrenia in Puerto Rican patients of Spanish descent.
Neuromolecular medicine - 1 Mar 2012
Bespalova Irina N, Angelo Gary W, Ritter Ben P, Hunter Jason, Reyes-Rabanillo Maria L, Siever Larry J, Silverman Jeremy M
Abstract excerpt
ADAMTS12 belongs to the family of metalloproteinases that mediate a communication between specific cell types and play a key role in the regulation of normal tissue development, remodeling, and degradation. Members of this family have been implicated in neurodegenerative and neuroinflammatory, as well as in muscular-skeletal, cardiovascular, respiratory and renal diseases, and cancer. Several metalloproteinases...
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