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Article

Association analysis of potentially functional variants within 8p12 with schizophrenia in the Han Chinese population.

The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry - 1 Jan 2021

Chen Ruirui, Chen Jianhua, Gao Chengwen, Wu Chuanhong, Pan Dun, Zhang Jinmai, Zhou Juan, Wang Ke, Zhang Qian, Yang Qiangzhen, Jian Xuemin, Zhao Yalin, Wen Yanqin, Wang Zhuo, Shi Yongyong, Li Zhiqiang

Abstract excerpt

OBJECTIVES: Chromosome 8p12 was first identified as a schizophrenia (SCZ) risk locus in Chinese populations and replicated in European populations. However, the underlying functional variants still need to be further explored. In this study, we sought to identify plausible causal variants within this locus. METHODS: A total of 386 potentially functional variants from 29 genes within the 8p12 locus were analysed...

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PMID: 32129128
DOI: 10.1080/15622975.2020.1738550

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