Article
ADAMTSL3 as a candidate gene for schizophrenia: gene sequencing and ultra-high density association analysis by imputation.
Schizophrenia research - 1 Apr 2011
Dow David J, Huxley-Jones Julie, Hall Jamie M, Francks Clyde, Maycox Peter R, Kew James N C, Gloger Israel S, Mehta Nalini A L, Kelly Fiona M, Muglia Pierandrea, Breen Gerome, Jugurnauth Sarah, Pederoso Inti, St Clair David, Rujescu Dan, Barnes Michael R
Abstract excerpt
We previously reported an association with a putative functional variant in the ADAMTSL3 gene, just below genome-wide significance in a genome-wide association study of schizophrenia. As variants impacting the function of ADAMTSL3 (a disintegrin-like and metalloprotease domain with thrombospondin type I motifs-like-3) could illuminate a novel disease mechanism and a potentially specific target, we have used...
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