Article
Assessment of the correlation between TIMP4 SNPs and schizophrenia and autism spectrum disorders.
Molecular medicine reports - 1 Feb 2013
Yim Sung-Vin, Kim Su Kang, Park Hae Jeong, Jeon Hye Sook, Jo Byung Chul, Kang Won Sub, Lee Sang Min, Kim Jong Woo, Chung Joo-Ho
Abstract excerpt
Tissue inhibitors of metalloproteinases (TIMPs) are involved in synaptic plasticity, neuronal cell differentiation and neuroprotection in the central nervous system. To investigate whether TIMP4 polymorphisms are associated with schizophrenia and autism spectrum disorders (ASDs), 480 patients (schizophrenia, n=287; ASDs, n=193) and 296 controls were enrolled. Clinical symptoms of schizophrenia and ASDs were...
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