Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Non-synonymous variants in the AMACR gene are associated with schizophrenia.

Schizophrenia research - 1 Dec 2010

Bespalova Irina N, Durner Martina, Ritter Benjamin P, Angelo Gary W, Rossy-Fullana Enrique, Carrion-Baralt Jose, Schmeidler James, Silverman Jeremy M

Abstract excerpt

BACKGROUND: The AMACR gene is located in the schizophrenia susceptibility locus on chromosome 5p13, previously identified in a large Puerto Rican pedigree of Spanish origin. The AMACR-encoded protein is an enzyme involved in the metabolism of branched-chain fatty and bile acids. The enzyme deficiency causes structural and functional brain changes, and disturbances in fatty acid and oxidative phosphorylation...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3' Flanking Region
Share to 5' Flanking Region

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Family

Share to Open Reading Frames

Share to Puerto Rico

Share to Racemases and Epimerases

Share to Schizophrenia

Share to Siblings

Source

Open in PubMed Open full text

Identifiers

PMID: 20875727
DOI: 10.1016/j.schres.2010.08.040
PMCID: PMC2981684

Genes

AMACR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Non-synonymous variants in the AMACR gene are associated with schizophrenia.PMID 20875727Read ↗

Exome sequences of multiplex, multigenerational families reveal schizophrenia risk loci with potential implications for neurocognitive performance.Semantic proximity Read ↗

Rare and common variants analysis of the EMB gene in patients with schizophrenia.Semantic proximity Read ↗

The C allele of synonymous SNP (rs1142636, Asn170Asn) in SYN1 is a risk factor for the susceptibility of Korean female schizophrenia.Semantic proximity Read ↗

Genetic association of ACSM1 variation with schizophrenia and major depressive disorder in the Han Chinese population.Semantic proximity Read ↗

Methionine sulfoxide reductase: a novel schizophrenia candidate gene.Semantic proximity Read ↗

A polymorphism of the ABCA1 gene confers susceptibility to schizophrenia and related brain changes.Semantic proximity Read ↗

Genetic variations in the ADAMTS12 gene are associated with schizophrenia in Puerto Rican patients of Spanish descent.Semantic proximity Read ↗

The GABRB3 Polymorphism and its Association with Schizophrenia.Semantic proximity Read ↗

CACNA1C Polymorphism (rs2283291) Is Associated with Schizophrenia in Chinese Males: A Case-Control StudySemantic proximity Read ↗

Genetic analysis of common variants in the CMYA5 (cardiomyopathy-associated 5) gene with schizophrenia.Semantic proximity Read ↗

Association between CMYA5 gene polymorphisms and risk of schizophrenia in Uygur population and a meta-analysis.Semantic proximity Read ↗

A118G polymorphism of OPRM1 gene is associated with schizophrenia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.