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Epidermal growth factor receptor mutations in adenocarcinoma lung: Comparison of techniques for mutation detection.

Indian journal of pathology & microbiology - 1 Jan 2000

Shukla Saumya, Pandey Rahul K, Mishra Sridhar, Tripathi Suryakant, Garg Rajiv, Gupta Gaurav, Husain Nuzhat

Abstract excerpt

Background: Targeted therapy using tyrosine kinase inhibitors in cases of non-small-cell lung carcinoma (NSCLC) that harbor epidermal growth factor receptor (EGFR) mutations has drastically improved the overall survival rate. The current study estimated the frequency of EGFR mutations in the Indian population by analyzing the diagnostic parameters of various techniques available for the detection of these...

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PMID: 35435362
DOI: 10.4103/IJPM.IJPM_1096_20

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