EGFR mutations in non-small-cell lung cancer: analysis of a large series of cases and development of a rapid and sensitive method for diagnostic screening with potential implications on pharmacologic treatment.

doi:10.1200/JCO.2005.08.043

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

EGFR mutations in non-small-cell lung cancer: analysis of a large series of cases and development of a rapid and sensitive method for diagnostic screening with potential implications on pharmacologic treatment.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 Feb 2005

Marchetti Antonio, Martella Carla, Felicioni Lara, Barassi Fabio, Salvatore Simona, Chella Antonio, Camplese Pier P, Iarussi Teodorico, Mucilli Felice, Mezzetti Andrea, Cuccurullo Franco, Sacco Rocco, Buttitta Fiamma

Abstract excerpt

PURPOSE: It has been reported that EGFR mutations in lung carcinomas make the disease more responsive to treatment with tyrosine kinase inhibitors. We decided to evaluate the prevalence of EGFR mutations in a large series of non-small-cell lung carcinomas (NSCLCs) and to develop a rapid and sensitive screening method. PATIENTS AND METHODS We examined 860 consecutive NSCLC patients for EGFR mutations in exons 18,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Adenocarcinoma, Bronchiolo-Alveolar

Share to Aged

Share to Aged, 80 and over

Share to Carcinoma, Non-Small-Cell Lung

Share to ErbB Receptors

Share to Lung Neoplasms

Share to Polymorphism, Single-Stranded Conformational

Source

Open in PubMed

Identifiers

PMID: 15681531
DOI: 10.1200/JCO.2005.08.043

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

EGFR mutations in non-small-cell lung cancer: analysis of a large series of cases and development of a rapid and sensitive method for diagnostic screening with potential implications on pharmacologic treatment.PMID 15681531Read ↗

EGFR Testing in Advanced Non-Small-Cell Lung Cancer, A Mini-Review.Semantic proximity Read ↗

Epidermal growth factor receptor mutations in adenocarcinoma lung: Comparison of techniques for mutation detection.Semantic proximity Read ↗

EGFR mutation testing in non-small cell lung cancer (NSCLC).Semantic proximity Read ↗

Detection of common and less frequent EGFR mutations in cytological samples of lung cancer.Semantic proximity Read ↗

Rapid detection of epidermal growth factor receptor mutations in non-small cell lung cancer using real-time polymerase chain reaction with TaqMan-MGB probes.Semantic proximity Read ↗

[Status and clinicopathologic implication of epidermal growth factor receptor mutation in non-small cell carcinoma of lung].Semantic proximity Read ↗

Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers.Semantic proximity Read ↗

Detection of rare and novel EGFR mutations in NSCLC patients: Implications for treatment-decision.Semantic proximity Read ↗

[Detection of epidermal growth factor receptor gene mutations and its clinical significance in non-small cell lung cancers].Semantic proximity Read ↗

Mutational analysis in cytological specimens of advanced lung adenocarcinoma: a sensitive method for molecular diagnosis.Semantic proximity Read ↗

PCR-based testing for therapy-related EGFR mutations in patients with non-small cell lung cancer.Semantic proximity Read ↗

Molecular diagnosis of activating EGFR mutations in non-small cell lung cancer using mutation-specific antibodies for immunohistochemical analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.