Article
Application of a highly sensitive detection system for epidermal growth factor receptor mutations in plasma DNA.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Sept 2012
Nakamura Tomomi, Sueoka-Aragane Naoko, Iwanaga Kentaro, Sato Akemi, Komiya Kazutoshi, Kobayashi Naomi, Hayashi Shinichiro, Hosomi Toshiya, Hirai Mitsuharu, Sueoka Eisaburo, Kimura Shinya
Abstract excerpt
INTRODUCTION: : Detection of epidermal growth factor receptor (EGFR) mutations is indispensable to determine an appropriate lung cancer treatment. Although retreatment often prolongs survival, how to select the appropriate population for retreatment has not been clarified. METHODS: : We used novel methods to identify EGFR mutations: wild inhibiting polymerase chain reaction (PCR) and quenched probe system...
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