Article
New experimental data linking secondhand smoke exposure to lung cancer in nonsmokers.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 May 2012
Kim Sang-In, Yoon Jae-In, Tommasi Stella, Besaratinia Ahmad
Abstract excerpt
Secondhand smoke (SHS) exposure is a known risk factor for lung cancer development in lifelong nonsmokers; however, the mechanistic involvement of SHS in the genesis of this malignancy remains elusive. The present study is the first comprehensive investigation of SHS mutagenicity in vivo, in which we have established the mutagenic effects of SHS in transgenic Big Blue mice, and subsequently found correlations...
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