Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Organ specificity of the bladder carcinogen 4-aminobiphenyl in inducing DNA damage and mutation in mice.

Cancer prevention research (Philadelphia, Pa.) - 1 Feb 2012

Yoon Jae-In, Kim Sang-In, Tommasi Stella, Besaratinia Ahmad

Abstract excerpt

Aromatic amines are a widespread class of environmental contaminants present in various occupational settings and tobacco smoke. Exposure to aromatic amines is a major risk factor for bladder cancer development. The etiologic involvement of aromatic amines in the genesis of bladder cancer is attributable to their ability to form DNA adducts, which upon eluding repair and causing mispairing during replication, may...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinogens
Share to DNA Adducts
Share to DNA Damage

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mutagenesis

Share to Organ Specificity

Share to Survival Rate

Share to Urinary Bladder Neoplasms

Share to Viral Proteins

Source

Identifiers

PMID: 22086680
DOI: 10.1158/1940-6207.CAPR-11-0309

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Organ specificity of the bladder carcinogen 4-aminobiphenyl in inducing DNA damage and mutation in mice.PMID 22086680Read ↗

BBN-driven urinary bladder cancer mouse model.Semantic proximity Read ↗

4-aminobiphenyl is a major etiological agent of human bladder cancer: evidence from its DNA binding spectrum in human p53 gene.Semantic proximity Read ↗

Understanding the Gender Disparity in Bladder Cancer Risk: The Impact of Sex Hormones and Liver on Bladder Susceptibility to CarcinogensSemantic proximity Read ↗

4-Aminobiphenyl and DNA reactivity: case study within the context of the 2006 IPCS Human Relevance Framework for Analysis of a cancer mode of action for humans.Semantic proximity Read ↗

Spectrum of mutations in kidney, stomach, and liver from lacI transgenic mice recovered after treatment with tris(2,3-dibromopropyl)phosphate.Semantic proximity Read ↗

Mutagenicity of N-hydroxy-4-aminobiphenyl in human TP53 knock-in (Hupki) mouse embryo fibroblasts.Semantic proximity Read ↗

Epidemiological models of carcinogenesis: the example of bladder cancer.Semantic proximity Read ↗

Studies on mammary carcinogenesis induced by a heterocyclic amine, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, in mice and rats.Semantic proximity Read ↗

DNA adduct levels in congenic rapid and slow acetylator mouse strains following chronic administration of 4-aminobiphenyl.Semantic proximity Read ↗

Cytotoxicity and genotoxicity of the carcinogen aristolochic acid I (AA-I) in human bladder RT4 cells.Semantic proximity Read ↗

Frequency and spectrum of lacI mutations in the liver of Big Blue mice following the administration of genotoxic carcinogens singly and in series.Semantic proximity Read ↗

Acrylamide-induced carcinogenicity in mouse lung involves mutagenicity: cII gene mutations in the lung of big blue mice exposed to acrylamide and glycidamide for up to 4 weeks.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.