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Article

Pfcrt haplotypes and the evolutionary history of chloroquine-resistant Plasmodium falciparum.

Memorias do Instituto Oswaldo Cruz - 1 Feb 2012

Awasthi Gauri, Satya Prasad Godavarthi Bhogendra Krishna, Satya Godavarthi Bhogendra Krishna, Das Aparup

Abstract excerpt

Mutations in the Pfcrt gene that change the resulting amino acids and form different haplotypes are common and correlate with the prevalence of chloroquine resistant (CQR) field isolates of the malaria parasite, Plasmodium falciparum. This correlation provides opportunities to infer the global evolutionary history of CQ resistance by analysing CQR Pfcrt haplotype data. We collated data on the Pfcrt haplotypes...

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PMID: 22310546
DOI: 10.1590/s0074-02762012000100018

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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