Article
Global assessment of genetic paradigms of Pvmdr1 mutations in chloroquine-resistant Plasmodium vivax isolates.
Transactions of the Royal Society of Tropical Medicine and Hygiene - 7 May 2020
Spotin Adel, Mahami-Oskouei Mahmoud, Ahmadpour Ehsan, Parsaei Mahdi, Rostami Ali, Emami Shima, Gholipour Saba, Farmani Mostafa
Abstract excerpt
BACKGROUND: Chloroquine (CQ) is generally prescribed as the front-line antimalarial drug of choice to treat Plasmodium vivax infections; however, some clinical CQ-resistant P. vivax isolates have been indigenously reported around the world during the last decade. METHODS: In this study, P. vivax isolates (n=52) were obtained from autochthonous samples in southeast Iran during 2015-2017. The genomic DNA of samples...
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