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Article

Diversity of Plasmodium falciparum chloroquine resistance transporter (pfcrt) exon 2 haplotypes in the Pacific from 1959 to 1979.

PloS one - 1 Jan 2012

Chan Chim W, Spathis Rita, Reiff Dana M, McGrath Stacy E, Garruto Ralph M, Lum J Koji

Abstract excerpt

Nearly one million deaths are attributed to malaria every year. Recent reports of multi-drug treatment failure of falciparum malaria underscore the need to understand the molecular basis of drug resistance. Multiple mutations in the Plasmodium falciparum chloroquine resistance transporter (pfcrt) are involved in chloroquine resistance, but the evolution of complex haplotypes is not yet well understood. Using over...

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Identifiers

PMID: 22272308
DOI: 10.1371/journal.pone.0030213
PMCID: PMC3260253

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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