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Article

Differences in nucleotide excision repair capacity between newly diagnosed colorectal cancer patients and healthy controls.

Mutagenesis - 1 Mar 2012

Slyskova Jana, Naccarati Alessio, Pardini Barbara, Polakova Veronika, Vodickova Ludmila, Smerhovsky Zdenek, Levy Miroslav, Lipska Ludmila, Liska Vaclav, Vodicka Pavel

Abstract excerpt

Alteration of DNA integrity is a potential cause of cancer and it is assumed that reduced DNA repair capacity and accumulation of DNA damage may represent intermediate markers in carcinogenesis. In this case-control study, DNA damage and nucleotide excision repair capacity (NER-DRC) were assessed in association with sporadic colorectal cancer (CRC). Both parameters were quantified by comet assay in blood cells of...

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Identifiers

PMID: 22294771
DOI: 10.1093/mutage/ger088

Genes

XPC
XPA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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