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Article

Nucleotide excision repair and response and survival to chemotherapy in colorectal cancer patients.

Pharmacogenomics - 1 May 2016

Kap Elisabeth J, Popanda Odilia, Chang-Claude Jenny

Abstract excerpt

Several new chemotherapeutic agents have become available for the treatment of colorectal cancer, which has led to increased complexity in treatment planning. Treatment decision making for individual patients could be facilitated if guided by predictive and prognostic markers. As most cytotoxic drugs induce DNA damage, the DNA damage repair pathways hold potential for yielding such biomarkers. Here, we review the...

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PMID: 27183147
DOI: 10.2217/pgs-2015-0017

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