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Article

An association selected polymorphisms of XRCC1, OGG1 and MUTYH gene and the level of efficiency oxidative DNA damage repair with a risk of colorectal cancer.

Mutation research - 1 Jan 2000

Przybylowska Karolina, Kabzinski Jacek, Sygut Andrzej, Dziki Lukasz, Dziki Adam, Majsterek Ireneusz

Abstract excerpt

Oxidative damage has been implicated in the pathogenesis of colorectal cancer (CRC). The base excision repair (BER) pathway is the major DNA repair pathway for oxidative DNA damage and genetic variation associated with impaired BER might thus increase a risk of CRC. In this work, we evaluated associations between the repair efficiency of oxidative DNA lesions and single-nucleotide polymorphisms of BER genes: the...

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Source

Identifiers

PMID: 23618615
DOI: 10.1016/j.mrfmmm.2013.04.002

Genes

MUTYH
OGG1
XRCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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