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Article

The C/A polymorphism in intron 11 of the XPC gene plays a crucial role in the modulation of an individual's susceptibility to sporadic colorectal cancer.

Molecular biology reports - 1 Jan 2012

Gil Justyna, Ramsey Dave, Stembalska Agnieszka, Karpinski Pawel, Pesz Karolina A, Laczmanska Izabela, Leszczynski Przemyslaw, Grzebieniak Zygmunt, Sasiadek Maria Malgorzata

Abstract excerpt

Epidemiological data show that colorectal cancer (CRC) is the second most frequent malignancy worldwide. The involvement of "minor impact genes" such as XME and DNA-repair genes in the etiology of sporadic cancer has been postulated by other authors. We focused on analyzing polymorphisms in DNA-repair genes in CRC. We considered the following genes involved in DNA-repair pathways: base excision repair (OGG1...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21559836
DOI: 10.1007/s11033-011-0767-5

Genes

XPC
ERCC1
OGG1
XPA
XRCC1
XRCC3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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