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Article

Lys751Gln XPD and Arg399Gln XRCC1 in Romanians. Association with sporadic colorectal cancer risk and different stages of carcinomas.

Chirurgia (Bucharest, Romania : 1990) - 1 Jan 2000

Procopciuc L M, Osian G

Abstract excerpt

BACKGROUND: DNA repair processes involved the removal of modified bases through the base excision repair (BER) pathway and removal of damaged nucleotides through the nucleotide excision repair (NER) pathways. METHODS: in order to determine the association between XPD(Lys751Gln) and XRCC1 (Arg399Gln) SNPs and the risk of CRC as well as tumor grade and stages in Romanians we genotyped using PCR-RFLP methods 150...

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Identifiers

PMID: 24157118

Genes

XRCC1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Lys751Gln XPD and Arg399Gln XRCC1 in Romanians. Association with sporadic colorectal cancer risk and different stages of carcinomas.PMID 24157118Read ↗

Colorectal Cancer Carcinogenesis: a Multivariate Genetic Model in a Cohort of Romanian Population.Semantic proximity Read ↗

No association between XRCC3 Thr241Met and XPD Lys751Gln polymorphisms and the risk of colorectal cancer in West Algerian population: a case-control study.Semantic proximity Read ↗

Association of XRCC1 Arg399Gln Polymorphism with Colorectal Cancer Risk: A HuGE Meta Analysis of 35 Studies.Semantic proximity Read ↗

Polymorphisms of the XRCC1, XRCC3 and XPD genes and risk of colorectal adenoma and carcinoma, in a Norwegian cohort: a case control study.Semantic proximity Read ↗

Association of XPD Lys751Gln gene polymorphism with susceptibility and clinical outcome of colorectal cancer in Pakistani population: a case-control pharmacogenetic study.Semantic proximity Read ↗

XRCC1 Arg399Gln Genetic Variant Increases Colorectal Cancer Susceptibility: A Comprehensive Meta-Analysis.Semantic proximity Read ↗

Association of APE1 and hOGG1 polymorphisms with colorectal cancer risk in a Turkish population.Semantic proximity Read ↗

Inheritance of the 194Trp and the 399Gln variant alleles of the DNA repair gene XRCC1 are associated with increased risk of early-onset colorectal carcinoma in Egypt.Semantic proximity Read ↗

No association of XRCC1 polymorphisms Arg194Trp and Arg399Gln with colorectal cancer risk.Semantic proximity Read ↗

Functional Polymorphisms in DNA Repair Genes Are Associated with Sporadic Colorectal Cancer Susceptibility and Clinical OutcomeSemantic proximity Read ↗

The C/A polymorphism in intron 11 of the XPC gene plays a crucial role in the modulation of an individual's susceptibility to sporadic colorectal cancer.Semantic proximity Read ↗

Genetic polymorphisms in XRCC1 genes and colorectal cancer susceptibility.Semantic proximity Read ↗

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