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Article

Genetic variations associated with gemcitabine treatment outcome in pancreatic cancer

5 Oct 2016

Abstract excerpt

BACKGROUND: Pancreatic cancer is a rapidly fatal disease with gemcitabine remaining the first-line therapy. We performed a genotype-phenotype association study to identify biomarkers for predicting gemcitabine treatment outcome. MATERIALS AND METHODS: We selected the top 200 single nucleotide polymorphisms (SNPs) identified from our previous genome-wide association study to associate with overall survival using...

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PMID: 27749787
DOI: 10.1097/fpc.0000000000000241

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