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Article

Cytidine deaminase polymorphism predicts toxicity of gemcitabine-based chemotherapy.

Gene - 15 Mar 2015

Ding Xiangxiang, Chen Wenwei, Fan Haijian, Zhu Bin

Abstract excerpt

BACKGROUND: The aim of this study was to ascertain whether single nucleotide polymorphisms of cytidine deaminase (CDA), a key enzyme in the metabolism pathway of gemcitabine, could predict clinical outcomes of cancer patients with gemcitabine-based chemotherapy. METHODS: We searched MEDLINE and EMBASE up to January 2013 to identify eligible studies. A rigorous quality assessment of eligible studies was conducted...

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Source

Identifiers

PMID: 25582275
DOI: 10.1016/j.gene.2015.01.010

Genes

CDA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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