Article
A major recombination hotspot in the XqYq pseudoautosomal region gives new insight into processing of human gene conversion events.
Human molecular genetics - 1 May 2012
Sarbajna Shriparna, Denniff Matthew, Jeffreys Alec J, Neumann Rita, Soler Artigas María, Veselis Amelia, May Celia A
Abstract excerpt
Recombination plays a fundamental role in meiosis. Non-exchange gene conversion (non-crossover, NCO) may facilitate homologue pairing, while reciprocal crossover (CO) physically connects homologues so they orientate appropriately on the meiotic spindle. In males, X-Y homologous pairing and exchange occurs within the two pseudoautosomal regions (PARs) together comprising <5% of the human sex chromosomes....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.