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Article

Transmission distortion affecting human noncrossover but not crossover recombination: a hidden source of meiotic drive.

PLoS genetics - 1 Feb 2014

Odenthal-Hesse Linda, Berg Ingrid L, Veselis Amelia, Jeffreys Alec J, May Celia A

Abstract excerpt

Meiotic recombination ensures the correct segregation of homologous chromosomes during gamete formation and contributes to DNA diversity through both large-scale reciprocal crossovers and very localised gene conversion events, also known as noncrossovers. Considerable progress has been made in understanding factors such as PRDM9 and SNP variants that influence the initiation of recombination at human hotspots but...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24516398
DOI: 10.1371/journal.pgen.1004106
PMCID: PMC3916235

Genes

PRDM9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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