Article
Meta-analysis of the association of the C677T polymorphism of the methylenetetrahydrofolate reductase gene with hyperuricemia.
Annals of nutrition & metabolism - 1 Jan 2012
Wei Wen, Liu Sheng-yuan, Zeng Fang-fang, Ma Ling, Li Ke-shen, Wang Bin-you
Abstract excerpt
BACKGROUND: The association between the MTHFR C677T polymorphism and hyperuricemia has been investigated in several studies. Although these epidemiological studies have shown that genetic factors are determinants of serum uric acid levels, the power of the association is weak due to the small sample size. METHODS: To study whether the MTHFR C677T polymorphism has an effect on hyperuricemia, we carried out a...
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