Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of methylenetetrahydrofolate reductase (C677T) polymorphism with hyperuricemia.

Nutrition, metabolism, and cardiovascular diseases : NMCD - 1 Jul 2007

Golbahar Jamal, Aminzadeh Mohammad A, Al-Shboul Qasim M, Kassab Salah, Rezaian Golam R

Abstract excerpt

BACKGROUND AND AIMS: Homozygosity for the thermolabile variant of 5,10-methylene tetrahydrofolate reductase (C677T) has been suggested to be positively associated with the risk of vascular disease and neural tube defects. In addition, recent studies have suggested that elevated serum uric acid predicts ischemic heart disease, and epidemiological data on ethnic groups have suggested that genetic factors are...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Homozygote
Share to Hyperuricemia

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Linear Models

Share to Methylenetetrahydrofolate Reductase (NADPH2)

Share to Odds Ratio

Share to Risk Assessment

Share to Uric Acid

Source

Identifiers

PMID: 17010581
DOI: 10.1016/j.numecd.2006.02.002

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of methylenetetrahydrofolate reductase (C677T) polymorphism with hyperuricemia.PMID 17010581Read ↗

Meta-analysis of the association of the C677T polymorphism of the methylenetetrahydrofolate reductase gene with hyperuricemia.Semantic proximity Read ↗

The C677T mutation in the methylene tetrahydrofolate reductase gene increases serum uric acid in elderly men.Semantic proximity Read ↗

The C677 mutation in methylene tetrahydrofolate reductase gene: correlation with uric acid and cardiovascular risk factors in elderly Korean men.Semantic proximity Read ↗

Significant association between methylenetetrahydrofolate reductase 677T allele and hyperuricemia among adult Japanese subjects.Semantic proximity Read ↗

Association of uricemia with biochemical and dietary factors in human adults with metabolic syndrome genotyped to C677T polymorphism in the methylenetetrahydrofolate reductase gene.Semantic proximity Read ↗

Polymorphism of methylenetetrahydrofolate reductase gene (C677T MTHFR) is not a confounding factor of the relationship between serum uric acid level and the prevalence of hypertension in Japanese men.Semantic proximity Read ↗

Distribution of 5,10-methylenetetrahydrofolate reductase (C667T) polymorphism and its association with red blood cell 5-methyltetrahydrofolate in the healthy Iranians.Semantic proximity Read ↗

Prevalence of the methylenetetrahydrofolate reductase 677C > T mutation in the Mediterranean Spanish population. Association with cardiovascular risk factors.Semantic proximity Read ↗

Thermolabile methylenetetrahydrofolate reductase polymorphism (C677T) and total homocysteine concentration among African-American and white women.Semantic proximity Read ↗

The TT genotype of the C677T polymorphism in the methylentetrahydrofolate reductase as a risk factor in thrombotic microangiopathies: results from a pilot study.Semantic proximity Read ↗

Genetically Elevated Serum Uric Acid and Renal Function in an Apparently Healthy Population.Semantic proximity Read ↗

Thermolabile variant of 5,10-methylenetetrahydrofolate reductase associated with low red-cell folates: implications for folate intake recommendations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.