Article
The C677 mutation in methylene tetrahydrofolate reductase gene: correlation with uric acid and cardiovascular risk factors in elderly Korean men.
Journal of Korean medical science - 1 Apr 2004
Hong Young Seoub, Lee Myeong Jin, Kim Kyeong Hee, Lee Sang Hwa, Lee Yong Hwan, Kim Byoung Gwon, Jeong Baekgeun, Yoon Hyeong Ryeol, Nishio Hisahide, Kim Joon Youn
Abstract excerpt
The C677T mutation in the methylene tetrahydrofolate reductase (MTHFR) gene results in elevated homocysteine levels and, presumably, in increased cardiovascular risk. Moreover, elevated homocysteine levels are reportedly associated with high serum uric acid levels. We evaluated the MTHFR genotype and a panel of biochemical, hematological variables, and lifestyle characteristics in 327 elderly Korean men (age...
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