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Article

Association of methylenetetrahydrofolate reductase gene C677T polymorphism with polycystic ovary syndrome risk: a systematic review and meta-analysis update.

European journal of obstetrics, gynecology, and reproductive biology - 1 Jan 2014

Fu Li-yuan, Dai Li-meng, Li Xiao-gang, Zhang Kun, Bai Yun

Abstract excerpt

OBJECTIVES: To re-estimate the association between methylenetetrahydrofolate reductase gene (MTHFR) C677T polymorphism and polycystic ovary syndrome (PCOS) risk by critically reviewing, analyzing and updating the current evidence. MTHFR C677T polymorphism has been studied as a possible risk factor for a variety of common conditions including heart disease, stroke and hypertension. Its association with PCOS was...

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Source

Identifiers

PMID: 24192663
DOI: 10.1016/j.ejogrb.2013.10.001

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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