Article
Genetic impact on uric acid concentration and hyperuricemia in the Japanese population.
Journal of atherosclerosis and thrombosis - 1 Jan 2013
Takeuchi Fumihiko, Yamamoto Ken, Isono Masato, Katsuya Tomohiro, Akiyama Koichi, Ohnaka Keizo, Rakugi Hiromi, Yamori Yukio, Ogihara Toshio, Takayanagi Ryoichi, Kato Norihiro
Abstract excerpt
AIM: Using general Japanese populations, we performed a replication study of genetic loci previously identified in European-descent populations as being associated with uric acid and gout. The relative contribution of non-genetic and genetic factors to the variances in serum uric acid concentration was then evaluated. METHODS: Seven single nucleotide polymorphisms (SNPs) were genotyped from 7 candidate loci...
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