Influence of Genetic and Non-Genetic Risk Factors for Serum Uric Acid Levels and Hyperuricemia in Mexicans.

doi:10.3390/nu11061336

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Influence of Genetic and Non-Genetic Risk Factors for Serum Uric Acid Levels and Hyperuricemia in Mexicans.

Nutrients - 14 Jun 2019

Rivera-Paredez Berenice, Macías-Kauffer Luis, Fernandez-Lopez Juan Carlos, Villalobos-Comparán Marisela, Martinez-Aguilar Mayeli M, de la Cruz-Montoya Aldo, Ramírez-Salazar Eric G, Villamil-Ramírez Hugo, Quiterio Manuel, Ramírez-Palacios Paula, Romero-Hidalgo Sandra, Villarreal-Molina María Teresa, Denova-Gutiérrez Edgar, Flores Yvonne N, Canizales-Quinteros Samuel, Salmerón Jorge, Velázquez-Cruz Rafael

Abstract excerpt

Risk of hyperuricemia is modified by genetic and environmental factors. Our aim was to identify factors associated with serum uric acid levels and hyperuricemia in Mexicans. A pilot Genome-wide association study GWAS was performed in a subgroup of participants (n = 411) from the Health Workers Cohort Study (HWCS). Single nucleotide polymorphisms (SNPs) associated with serum uric acid levels were validated in all...

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PMID: 31207883
DOI: 10.3390/nu11061336
PMCID: PMC6627998

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ABCG2
SLC2A9

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