Article
Polymorphism of methylenetetrahydrofolate reductase gene (C677T MTHFR) is not a confounding factor of the relationship between serum uric acid level and the prevalence of hypertension in Japanese men.
Circulation journal : official journal of the Japanese Circulation Society - 1 Jan 2006
Lwin Htay, Yokoyama Tetsuji, Yoshiike Nobuo, Saito Kyoko, Yamamoto Akio, Date Chigusa, Tanaka Heizo
Abstract excerpt
BACKGROUND: The association between serum uric acid (UA) and the prevalence of hypertension, and the relationship between methylenetetrahydrofolate reductase (MTHFR) polymorphism and hypertension remains unclear. The aim of the present study was to investigate whether the C677T MTHFR mutation genotype (VV) is independently associated with the prevalence of hypertension or blood pressure (BP), and examined any...
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