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Article

Genetic variants of SLC17A1 are associated with cholesterol homeostasis and hyperhomocysteinaemia in Japanese men.

Scientific reports - 3 Nov 2015

Koyama Teruhide, Matsui Daisuke, Kuriyama Nagato, Ozaki Etsuko, Tanaka Keitaro, Oze Isao, Hamajima Nobuyuki, Wakai Kenji, Okada Rieko, Arisawa Kokichi, Mikami Haruo, Shimatani Keiichi, Hirata Akie, Takashima Naoyuki, Suzuki Sadao, Nagata Chisato, Kubo Michiaki, Tanaka Hideo

Abstract excerpt

Hyperuricaemia is an undisputed and highly predictive biomarker for cardiovascular risk. SLC17A1, expressed in the liver and kidneys, harbours potent candidate single nucleotide polymorphisms that decrease uric acid levels. Therefore, we examined SLC17A1 polymorphisms (rs1165196, rs1179086, and rs3757131), which might suppress cardiovascular risk factors and that are involved in liver functioning, via a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Cholesterol, HDL

Cholesterol, LDL

Hyperhomocysteinemia

Logistic Models

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PMID: 26524967
DOI: 10.1038/srep15888
PMCID: PMC4630628

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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