Article
Significant association between methylenetetrahydrofolate reductase 677T allele and hyperuricemia among adult Japanese subjects.
Nutrition research (New York, N.Y.) - 1 Oct 2009
Itou Simon, Goto Yasuyuki, Suzuki Koji, Kawai Sayo, Naito Mariko, Ito Yoshinori, Hamajima Nobuyuki
Abstract excerpt
It is well known that high serum uric acid (SUA) is the cause of gout and a risk factor of cardiovascular diseases. Although SUA is thought to have an association with folate metabolism through elevated production and/or damaged renal excretion, studies on functional polymorphisms of folate metabolizing are still limited, showing inconsistent findings. We hypothesized that hyperuricemia would be associated with...
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