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Article

3'-UTR and functional secretor haplotypes in mannose-binding lectin 2 are associated with increased colon cancer risk in African Americans.

Cancer research - 15 Mar 2012

Zanetti Krista A, Haznadar Majda, Welsh Judith A, Robles Ana I, Ryan Bríd M, McClary Andrew C, Bowman Elise D, Goodman Julie E, Bernig Toralf, Chanock Stephen J, Harris Curtis C

Abstract excerpt

Because chronic intestinal inflammation is a risk factor for colorectal cancer, we hypothesized that genetic variants of inflammatory mediators, such as mannose-binding lectin 2 (MBL2), are associated with colon cancer susceptibility. Here, we report the association of 24 MBL2 single-nucleotide polymorphisms (SNP) and corresponding haplotypes with colon cancer risk in a case-control study. Four SNPs in the...

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Identifiers

PMID: 22282660
DOI: 10.1158/0008-5472.CAN-11-3073
PMCID: PMC3306468

Genes

MBL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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3'-UTR and functional secretor haplotypes in mannose-binding lectin 2 are associated with increased colon cancer risk in African Americans.PMID 22282660Read ↗

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