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Article

Lung cancer survival and functional polymorphisms in MBL2, an innate-immunity gene.

Journal of the National Cancer Institute - 19 Sept 2007

Pine Sharon R, Mechanic Leah E, Ambs Stefan, Bowman Elise D, Chanock Stephen J, Loffredo Christopher, Shields Peter G, Harris Curtis C

Abstract excerpt

BACKGROUND: The relationship among chronic inflammation, innate immunity, and cancer is well established. Mannose-binding lectin (MBL) is a key player in innate immunity. Five polymorphisms in the promoter and first exon of the MBL2 gene alter the expression and function of MBL in humans and are...

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Source

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Identifiers

PMID: 17848669
DOI: 10.1093/jnci/djm128
PMCID: PMC6278934

Genes

MBL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17848669-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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