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Article

Association of genetic variants of mannan-binding (MBL) lectin-2 gene, MBL levels and function in ulcerative colitis and Crohn's disease.

Innate immunity - 1 Dec 2011

Sivaram G, Tiwari Santosh K, Bardia Avinash, Manoj G, Santhosh B, Saikant R, Aejaz Habeeb, Vishnupriya S, Khan Aleem A, Habibullah Cm

Abstract excerpt

Ulcerative colitis and Crohn's disease are the two major forms of inflammatory bowel disease (IBD). A series of reports have hypothesized interplay of genetic and environmental factors in the pathogenesis of IBD. Polymorphism in the mannan-binding lectin-2 (MBL-2) gene is known to affect the structural assembly and function thereby predisposing subjects to various diseases. The present study was designed to...

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Identifiers

PMID: 21088049
DOI: 10.1177/1753425910384531

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