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Article

Fucosyltransferase 2 Mutations Are Associated With a Favorable Clinical Course in Crohn's Disease.

Journal of clinical gastroenterology - 1 Mar 2022

Battat Robert, Qatomah Abdulrahman, Kopylov Uri, Wyse Jonathan, Cohen Albert, Afif Waqqas, Lakatos Peter L, Seidman Ernest, Bitton Alain, Bessissow Talat

Abstract excerpt

BACKGROUND: Fucosyltransferase 2 (FUT2) participates in intestinal antigen secretion and bacterial adherence. FUT2 homozygous nonsense mutations (FUT2M) and subsequent nonsecretor status is associated with Crohn's disease (CD). The common null allele is rs601338. We assessed the relationship between FUT2M and disease course. METHODS: In consecutive adult CD outpatients, clinical, biochemical, and genetic data...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34739405
DOI: 10.1097/MCG.0000000000001626

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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