Article
The mannose-binding lectin (MBL2) haplotype and breast cancer: an association study in African-American and Caucasian women.
Carcinogenesis - 1 Apr 2007
Bernig Toralf, Boersma Brenda J, Howe Tiffany M, Welch Robert, Yadavalli Sunita, Staats Brian, Mechanic Leah E, Chanock Stephen J, Ambs Stefan
Abstract excerpt
Common genetic variants in cancer-related genes contribute to breast cancer. The innate immune system plays a crucial role in the immune surveillance against malignancies, thus it is plausible that genetic variations in key genes of the innate immunity such as the mannose-binding lectin (MBL), MBL2, could influence the risk for breast cancer. We investigated the association of MBL2 genotypes with breast cancer...
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