Article
The splicing factor SR45 affects the RNA-directed DNA methylation pathway in Arabidopsis.
Epigenetics - 1 Jan 2012
Ausin Israel, Greenberg Maxim V C, Li Carey Fei, Jacobsen Steven E
Abstract excerpt
Cytosine DNA methylation is an epigenetic mark frequently associated with silencing of genes and transposons. In Arabidopsis, the establishment of cytosine DNA methylation is performed by DOMAINS REARRANGED METHYLTRANSFERASE 2 (DRM2). DRM2 is guided to target sequences by small interfering RNAs (siRNAs) in a pathway termed RNA-directed DNA methylation (RdDM). We performed a screen for mutants that affect the...
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