Article
RNAi, DRD1, and histone methylation actively target developmentally important non-CG DNA methylation in arabidopsis.
PLoS genetics - 2 Jun 2006
Chan Simon W-L, Henderson Ian R, Zhang Xiaoyu, Shah Govind, Chien Jason S-C, Jacobsen Steven E
Abstract excerpt
Cytosine DNA methylation protects eukaryotic genomes by silencing transposons and harmful DNAs, but also regulates gene expression during normal development. Loss of CG methylation in the Arabidopsis thaliana met1 and ddm1 mutants causes varied and stochastic developmental defects that are often inherited independently of the original met1 or ddm1 mutation. Loss of non-CG methylation in plants with combined...
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