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Article

Hippocampal BDNF expression in a tau transgenic mouse model.

Current Alzheimer research - 1 May 2012

Burnouf Sylvie, Belarbi Karim, Troquier Laetitia, Derisbourg Maxime, Demeyer Dominique, Leboucher Antoine, Laurent Cyril, Hamdane Malika, Buee Luc, Blum David

Abstract excerpt

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by extracellular accumulation of amyloid deposits and intracellular neurofibrillary tangles (NFT) composed of hyperphosphorylated Tau proteins. Brain-derived neurotrophic factor (BDNF) is a neurotrophic factor playing a critical role in hippocampal synaptic plasticity and memory and whose levels have been shown reduced in AD brains. While...

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Source

Identifiers

PMID: 22272617
DOI: 10.2174/156720512800492468

Genes

BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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