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Article

Variations in the BDNF gene in autopsy-confirmed Alzheimer's disease and dementia with Lewy bodies in Japan.

Dementia and geriatric cognitive disorders - 1 Jan 2006

Akatsu Hiroyasu, Yamagata Hidehisa D, Kawamata Jun, Kamino Kouzin, Takeda Masatoshi, Yamamoto Takayuki, Miki Tetsuro, Tooyama Ikuo, Shimohama Shun, Kosaka Kenji

Abstract excerpt

BACKGROUND/AIM: Brain-derived neurotrophic factor (BDNF) is associated with the hippocampus and the nigrostriatal dopaminergic function. Data showing that its level was reduced in Alzheimer's disease (AD) and Parkinson's disease (PD) suggested that the BDNF function must play an important role in the pathogenetics of these diseases. Indeed, variation in the BDNF gene may confer susceptibility to AD and PD...

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Identifiers

PMID: 16899999
DOI: 10.1159/000094933

Genes

BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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