Article

Stability of dentate gyrus granule cell mossy fiber BDNF protein expression with age and resistance of granule cells to Alzheimer’s disease neuropathology in a mouse model

2023-05-08

Abstract excerpt

<h4>ABSTRACT</h4> The neurotrophin brain-derived neurotrophic factor (BDNF) is important in development and maintenance of neurons and their plasticity. Hippocampal BDNF has been implicated Alzheimer’s disease (AD) because hippocampal levels in AD patients and AD animal models are consistently downregulated, suggesting that reduced BDNF contributes to AD. However, the location where hippocampal BDNF protein is mo...

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Literature Corpus work: 42b4a0a9-06d6-5932-a3d5-2d7d797386b8
DOI: 10.1101/2023.05.07.539742

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