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Article

Decreased levels of BDNF protein in Alzheimer temporal cortex are independent of BDNF polymorphisms.

Experimental neurology - 1 Jul 2005

Lee Jung, Fukumoto Hiroaki, Orne Jennifer, Klucken Jochen, Raju Susan, Vanderburg Charles R, Irizarry Michael C, Hyman Bradley T, Ingelsson Martin

Abstract excerpt

Levels of brain-derived neurotrophic factor (BDNF) are reduced in specific brain regions in Alzheimer's disease (AD) and BDNF gene polymorphisms have been suggested to influence AD risk, hippocampal function, and memory. We investigated whether the polymorphisms at the BDNF 196 and 270 loci were associated with AD in a clinical and neuropathological cohort of 116 AD cases and 77 control subjects. To determine how...

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Source

Identifiers

PMID: 15899246
DOI: 10.1016/j.expneurol.2005.01.026

Genes

BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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