Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Influence of obesity-susceptibility loci (MC4R and INSIG2) on the outcome of weight loss and amelioration of co-morbidity in obese patients treated by a gastric-bypass.

Bulletin de la Societe des sciences medicales du Grand-Duche de Luxembourg - 1 Jan 2011

Goergen M, Manzoni D, De Blasi V, Fabiano P, Poulain V, De Magistris L, Simonelli V, Dahan K, Azagra J-S

Abstract excerpt

BACKGROUND: Genome-wide association and linkage studies have identified multiple susceptibility loci for obesity. OBJECTIVE: We hypothesized that such loci may affect weight loss and comorbidity amelioration outcomes following a gastric-bypass. DESIGN: A total of 200 obese patients who underwent a gastric bypass surgery were genotyped for single-nucleotide polymorphisms (SNPs) in insulin induced gene 2 (INSIG2)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Diabetes Mellitus
Share to Follow-Up Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hypertension

Share to Intracellular Signaling Peptides and Proteins

Share to Laparoscopy

Share to Obesity

Share to Receptor, Melanocortin, Type 4

Share to Weight Loss

Source

Identifiers

PMID: 22272442

Genes

INSIG2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Influence of obesity-susceptibility loci (MC4R and INSIG2) on the outcome of weight loss and amelioration of co-morbidity in obese patients treated by a gastric-bypass.PMID 22272442Read ↗

High allelic burden of four obesity SNPs is associated with poorer weight loss outcomes following gastric bypass surgery.Semantic proximity Read ↗

Genetic risk score based on obesity-related genes and progression in weight loss after bariatric surgery: a 60-month follow-up study.Semantic proximity Read ↗

The Genetic Predisposition Score of Seven Obesity-Related Single Nucleotide Polymorphisms Is Associated with Better Metabolic Outcomes after Roux-en-Y Gastric Bypass.Semantic proximity Read ↗

A Clinical-Genetic Score for Predicting Weight Loss after Bariatric Surgery: The OBEGEN StudySemantic proximity Read ↗

Gastric inhibitory polypeptide receptor: association analyses for obesity of several polymorphisms in large study groups.Semantic proximity Read ↗

Interaction Effects of FTO and MC4R Polymorphisms on Total Body Weight Loss, Post-Surgery Weight, and Post-Body Mass Index after Bariatric Surgery.Semantic proximity Read ↗

Interplay of an Obesity-Based Genetic Risk Score with Dietary and Endocrine Factors on Insulin Resistance.Semantic proximity Read ↗

Genetic Correlates as a Predictor of Bariatric Surgery Outcomes after 1 YearSemantic proximity Read ↗

Genetic markers of abdominal obesity and weight loss after gastric bypass surgery.Semantic proximity Read ↗

A Genetic Risk Score Is Associated with Weight Loss Following Roux-en Y Gastric Bypass Surgery.Semantic proximity Read ↗

Association of genetic predisposition to obesity with type 2 diabetes risk in Han Chinese individuals.Semantic proximity Read ↗

Low-frequency Coding Variants Associated With Body Mass Index Affect the Success of Bariatric Surgery.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.