Article
Genetic risk score based on obesity-related genes and progression in weight loss after bariatric surgery: a 60-month follow-up study.
Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery - 1 Sept 2024
Mas-Bermejo Patricia, Azcona-Granada Natalia, Peña Elionora, Lecube Albert, Ciudin Andreea, Simó Rafael, Luna Alexis, Rigla Mercedes, Arenas Concepción, Caixàs Assumpta, Rosa Araceli
Abstract excerpt
BACKGROUND: Obesity is a polygenic multifactorial disease. Recent genome-wide association studies have identified several common loci associated with obesity-related phenotypes. Bariatric surgery (BS) is the most effective long-term treatment for patients with severe obesity. The huge variability in BS outcomes between patients suggests a moderating effect of several factors, including the genetic architecture of...
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