Article
A Genetic Risk Score Is Associated with Weight Loss Following Roux-en Y Gastric Bypass Surgery.
Obesity surgery - 1 Sept 2016
Bandstein Marcus, Voisin Sarah, Nilsson Emil K, Schultes Bernd, Ernst Barbara, Thurnheer Martin, Benedict Christian, Mwinyi Jessica, Schiöth Helgi B
Abstract excerpt
BACKGROUND: Currently, Roux-en Y gastric bypass (RYGB) is the most efficient therapy for severe obesity. Weight loss after surgery is, however, highly variable and genetically influenced. Genome-wide association studies have identified several single nucleotide polymorphisms (SNP) associated with body mass index (BMI) and waist-hip ratio (WHR). We aimed to identify two genetic risk scores (GRS) composed of...
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