Article
The Genetic Predisposition Score of Seven Obesity-Related Single Nucleotide Polymorphisms Is Associated with Better Metabolic Outcomes after Roux-en-Y Gastric Bypass.
Journal of nutrigenetics and nutrigenomics - 1 Jan 2016
Nicoletti Carolina Ferreira, Pinhel Marcela A Souza, de Oliveira Bruno Affonso Parenti, Marchini Julio Sergio, Salgado Junior Wilson, Silva Junior Wilson Araujo, Nonino Carla Barbosa
Abstract excerpt
BACKGROUND/AIMS: Genetic variants associated with obesity have cumulative effects on obesity risk and related phenotypes. This study aimed to estimate the contribution of a genetic predisposition score (GPS) calculated from 7 obesity-related polymorphisms to the improvement of biochemical parameters 1 year after Roux-en-Y gastric bypass (RYGB). METHODS: Obese patients (n = 150; aged 47.2 ± 10.5 years) were...
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