Article
Genetic markers of abdominal obesity and weight loss after gastric bypass surgery.
PloS one - 1 Jan 2021
Aasbrenn Martin, Svendstrup Mathilde, Schnurr Theresia M, Lindqvist Hansen Dorte, Worm Dorte, Balslev-Harder Marie, Grarup Niels, Burgdorf Kristoffer Sølvsten, Vestergaard Henrik, Pedersen Oluf, Ängquist Lars, Fenger Mogens, Sørensen Thorkild I A, Madsbad Sten, Hansen Torben
Abstract excerpt
BACKGROUND: Weight loss after bariatric surgery varies widely between individuals, partly due to genetic differences. In addition, genetic determinants of abdominal obesity have been shown to attenuate weight loss after dietary intervention with special attention paid to the rs1358980-T risk allele in the VEGFA locus. Here we aimed to test if updated genetic risk scores (GRSs) for adiposity measures and the...
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