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Article

Genomewide pharmacogenetics of bisphosphonate-induced osteonecrosis of the jaw: the role of RBMS3.

The oncologist - 1 Jan 2012

Nicoletti Paola, Cartsos Vassiliki M, Palaska Penelope K, Shen Yufeng, Floratos Aris, Zavras Athanasios I

Abstract excerpt

UNLABELLED: Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a serious adverse drug reaction. We conducted a genomewide association study to search for genetic variants with a large effect size that increase the risk for BRONJ. METHODS: We ascertained BRONJ cases according to the diagnostic criteria of the American Association of Oral and Maxillofacial Surgeons. We genotyped cases and a set of...

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Source

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Identifiers

PMID: 22267851
DOI: 10.1634/theoncologist.2011-0202
PMCID: PMC3286178

Genes

RBMS3
ABCC4
IGFBP7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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