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Article

A Genome-Wide Association Study of Bisphosphonate-Associated Atypical Femoral Fracture

20 Apr 2019

Abstract excerpt

Atypical femoral fracture is a well-documented adverse reaction to bisphosphonates. It is strongly related to duration of bisphosphonate use, and the risk declines rapidly after drug withdrawal. The mechanism behind bisphosphonate-associated atypical femoral fracture is unclear, but a genetic predisposition has been suggested. With the aim to identify common genetic variants that could be used for preemptive...

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PMID: 31006051
DOI: 10.1007/s00223-019-00546-9

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