New approach to analyze genetic and clinical data in bisphosphonate-induced osteonecrosis of the jaw.

doi:10.1111/j.1601-0825.2012.01912.x

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Article

New approach to analyze genetic and clinical data in bisphosphonate-induced osteonecrosis of the jaw.

Oral diseases - 1 Sept 2012

Balla B, Vaszilko M, Kósa J P, Podani J, Takács I, Tóbiás B, Nagy Z, Lazáry A, Lakatos P

Abstract excerpt

OBJECTIVES: Osteonecrosis of the jaw (ONJ) is a major complication associated with long-term use of bisphosphonates (BP). We aimed to investigate the effect of CYP2C8 rs1934951 SNP and its relationship to a number of clinical and biochemical factors in 46 Hungarian subjects with bisphosphonate-induced ONJ. METHODS: Blood samples were collected from each subject and genomic DNA was extracted. SNP analysis of...

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PMID: 22339777
DOI: 10.1111/j.1601-0825.2012.01912.x

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